CCL2

Ligand id: 771

Name: CCL2

Species: Human

Classification
Compound class Endogenous peptide in human, mouse or rat
Gene/Precursor
Gene symbol Gene name Species Precursor protein name Synonyms
CCL2 C-C motif chemokine ligand 2 Human chemokine (C-C motif) ligand 2 chemokine (C-C motif) ligand 2, GDCF-2, HC11, MCAF, MCP1, MCP-1, MGC9434, monocyte chemoattractant protein-1, monocyte chemotactic and activating factor, monocyte chemotactic protein 1, homologous to mouse Sig-je, monocyte secretory protein JE, SCYA2, small inducible cytokine A2 (monocyte chemotactic protein 1, homologous to mouse Sig-je), small inducible cytokine subfamily A (Cys-Cys), member 2, SMC-CF
Database Links
DrugBank Target P13500 (Hs)
Ensembl Gene ENSG00000108691 (Hs)
Entrez Gene 6347 (Hs)
OMIM 158105 (Hs)
RefSeq Protein NP_002973 (Hs)
UniProtKB P13500 (Hs)
Wikipedia CCL2 (Hs)
Comments
CCL2 (generally known as MCP-1) is a CC family chemokine. It acts via the G protein-coupled receptors CCR2 and CCR4.
Medical Relevance
Many physiological conditions/malfunctions have been considered to be associated with various MCP-1 gene polymorphisms. For further information see GeneRIFs