bococizumab

Ligand id: 7730

Name: bococizumab

Classification
Compound class Antibody
International Nonproprietary Names
INN number INN
9840 bococizumab
Synonyms
PF-04950615
RN-316
RN316
Database Links
Specialist databases
IMGT/mAb-DB 485
Other databases
Search PubMed clinical trials bococizumab
Search PubMed titles bococizumab
Search PubMed titles/abstracts bococizumab
Wikipedia Bococizumab
Comments
Bococizumab is an experimental monoclonal antibody directed against PCSK9 [1]. Anti-PCSK9 antibodies are under intense clinical lead scrutiny, as the successors to statins for the treatment of hyperlipidemia and associated atherosclerotic cardiovascular disease. Peptide sequences for this antibody are available from its IMGT link. Based on sequence alignment bococizumab relates to antibody clone L1L3 in patent US8080243, with SEQ IDs 53 and 54 matching the sequences in the INN record for bococizumab.