amuvatinib

Ligand id: 7932

Name: amuvatinib

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 5
Topological polar surface area 107.98
Molecular weight 447.14
XLogP 3.92
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
N-(1,3-benzodioxol-5-ylmethyl)-4-([1]benzoxolo[2,3-e]pyrimidin-4-yl)piperazine-1-carbothioamide
International Nonproprietary Names
INN number INN
9278 amuvatinib
Synonyms
MP 470
MP-470
MP470
Database Links
CAS Registry No. 850879-09-3
ChEMBL Ligand CHEMBL2103851
PubChem CID 11282283
Search Google for chemical match using the InChIKey FOFDIMHVKGYHRU-UHFFFAOYSA-N
Search Google for chemicals with the same backbone FOFDIMHVKGYHRU
Search PubMed clinical trials amuvatinib
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Comments
Amuvatinib is an orally bioavailable, multitargeted receptor tyrosine kinase inhibitor. Some bioactivity data may be associated with the hydrochloride salt (PubChem CID 67254077).