tabalumab

Ligand id: 8000

Name: tabalumab

Classification
Compound class Antibody
International Nonproprietary Names
INN number INN
9430 tabalumab
Synonyms
LY 2127399
LY2127399
Database Links
Specialist databases
IMGT/mAb-DB 385
Other databases
Search PubMed clinical trials tabalumab
Search PubMed titles tabalumab
Search PubMed titles/abstracts tabalumab
Wikipedia Tabalumab
Comments
Tabalumab is a monoclonal antibody directed against B-cell activating factor (BAFF, TNFSF13B). It was being developed as a treatment for autoimmune diseases [1] and B cell malignancies.
Peptide sequence and structural information for this antibody are available from its IMGT/mAb-db record. Peptide sequence BLAST search using the heavy chain variable region of tabalumab provides 100% match to a sequence covered by patent US7317089 [2], and to the antibody with designation 4A5-3.1.1-B4.