epratuzumab

Ligand id: 8088

Name: epratuzumab

Classification
Compound class Antibody
International Nonproprietary Names
INN number INN
7920 epratuzumab
Synonyms
90Y-DOTA-hLL2 | 90Y-epratuzumab tetraxetan | 90Y-hLL2 | AMG-412 | IMMU-hLL2 | LymphoCide® (proposed proprietary name)
Database Links
Specialist databases
IMGT/mAb-DB 40
Other databases
DrugBank Ligand DB04958
GtoPdb PubChem SID 249565768
Search PubMed clinical trials epratuzumab
Search PubMed titles epratuzumab
Search PubMed titles/abstracts epratuzumab
Wikipedia Epratuzumab
Comments
Epratuzumab is a humanized monoclonal antibody. It is derived from the murine IG2a monotclonal antibody, LL2 (EPB-2). Epratuzumab has antineoplastic and antiinflammatory actions [1].
The antibody can be conjugated with tetraxetan (DOTA) which allows chelation of radionucleotides such as yttrium-90 [5].