MABp1

Ligand id: 8089

Name: MABp1

Classification
Compound class Antibody
Synonyms
Xilonix® (proposed trade name)
Database Links
Specialist databases
IMGT/mAb-DB 544
Comments
MABp1 is an investigational fully human monoclonal antibody targeting IL-1α, with potential antiinflammatory action. This antibody is the first genuinely human monoclonal antibody to be produced directly from an affinity matured, human immune response. As MABp1 has not been subject to in vitro sequence modification it is predicted to have improved tolerability compared to antibodies that are 'humanised'.
A patent search suggest that Xilonix is the subject of WO2009148575 [3], although we do not have access to the peptide sequences of the antibody to confirm this.