CXCL1

Ligand id: 819

Name: CXCL1

Species: Human

Classification
Compound class Endogenous peptide in human, mouse or rat
Gene/Precursor
Gene symbol Gene name Species Precursor protein name Synonyms
CXCL1 C-X-C motif chemokine ligand 1 Human chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha), fibroblast secretory protein, FSP, GRO1, GRO1 oncogene (melanoma growth stimulating activity, alpha), GROa, MGSA, MGSA-a, NAP-3, SCYB1
Synonyms
GROα
melanocyte growth-stimulatory activity
MIP-2
Database Links
Ensembl Gene ENSG00000163739
Entrez Gene 2919
OMIM 155730
RefSeq Protein NP_001502
UniProtKB P09341 (Hs)
Wikipedia CXCL1
Comments
CXCL1 is a C-X-C motif chemokine expressed by macrophages, neutrophils and epithelial cells, that acts via the chemokine receptor CXCR2. CXCL1 is expressed by keratinocytes and endothelial cells at sites of epithelialization and neovascularization in the process of wound healing [2].