CXCL8

Ligand id: 821

Name: CXCL8

Species: Human

Classification
Compound class Endogenous peptide in human, mouse or rat
Ligand families/groups Chemokines
Gene/Precursor
Gene symbol Gene name Species Precursor protein name Synonyms
CXCL8 C-X-C motif chemokine ligand 8 Human interleukin 8 3-10C, alveolar macrophage chemotactic factor I, AMCF-I, b-ENAP, beta endothelial cell-derived neutrophil activating peptide, chemokine (C-X-C motif) ligand 8, CXCL8, GCP1, GCP-1, granulocyte chemotactic protein 1, IL8, IL-8, interleukin 8, K60, LECT, LUCT, lung giant cell carcinoma-derived chemotactic protein, lymphocyte derived neutrophil activating peptide, LYNAP, MDNCF, MONAP, monocyte-derived neutrophil-activating peptide, monocyte-derived neutrophil chemotactic factor, NAF, NAP1, NAP-1, neutrophil-activating peptide 1, SCYB8, TSG-1, tumor necrosis factor-induced gene 1
Synonyms
interleukin-8
Database Links
UniProtKB P10145 (Hs)
Wikipedia Interleukin_8
Comments
The CXCL8 (IL-8) chemokine is upregulated at sites of inflammation where it promotes neutrophil infiltration and activation. It can form homodimers and heterodimers with CXCL4.