CXCL8

Ligand id: 821

Name: CXCL8

Species: Human

Structure and Physico-chemical Properties

2D Structure
Classification
Compound class Endogenous peptide in human, mouse or rat
Gene/Precursor
Gene symbol Gene name Species Precursor protein name Synonyms
CXCL8 C-X-C motif chemokine ligand 8 Human interleukin 8 3-10C, alveolar macrophage chemotactic factor I, AMCF-I, b-ENAP, beta endothelial cell-derived neutrophil activating peptide, chemokine (C-X-C motif) ligand 8, CXCL8, GCP1, GCP-1, granulocyte chemotactic protein 1, IL8, IL-8, interleukin 8, K60, LECT, LUCT, lung giant cell carcinoma-derived chemotactic protein, lymphocyte derived neutrophil activating peptide, LYNAP, MDNCF, MONAP, monocyte-derived neutrophil-activating peptide, monocyte-derived neutrophil chemotactic factor, NAF, NAP1, NAP-1, neutrophil-activating peptide 1, SCYB8, TSG-1, tumor necrosis factor-induced gene 1
Synonyms
interleukin-8
Database Links
BindingDB Ligand 50291127
ChEMBL Ligand CHEMBL411250
PubChem CID 44357137
Search Google for chemical match using the InChIKey XKTZWUACRZHVAN-VADRZIEHSA-N
Search Google for chemicals with the same backbone XKTZWUACRZHVAN
UniProtKB P10145 (Hs)
Wikipedia Interleukin_8
Comments
The CXCL8 (IL-8) chemokine is upregulated at sites of inflammation where it promotes neutrophil infiltration and activation. It can form homodimers and heterodimers with CXCL4.

An alternative structure for this ligand is represented by CID 56947101.