anifrolumab

Ligand id: 8258

Name: anifrolumab

Classification
Compound class Antibody
International Nonproprietary Names
INN number INN
9800 anifrolumab
Synonyms
MDX-1333
MEDI-546
Database Links
Specialist databases
IMGT/mAb-DB 474
Other databases
Search PubMed clinical trials anifrolumab
Search PubMed titles anifrolumab
Search PubMed titles/abstracts anifrolumab
Wikipedia Anifrolumab
Comments
Anifrolumab is a monoclonal antibody targeting IFNAR1 (the receptor for α, β and ω interferons), being developed by the MedImmune subsidiary of AstraZeneca as a treatment for systemic lupus erythematosus (SLE).
Peptide sequence and structural information for this antibody are available from its IMGT/mAb-db record. [3]. Sequence BLAST using the heavy and light chain variable regions of anifrolumab provides 100% matches to sequences patented with application US7662381 [3]. The sequence matches identify anifrolumab as clone 11E2 in the patent.