milatuzumab

Ligand id: 8267

Name: milatuzumab

Classification
Compound class Antibody
International Nonproprietary Names
INN number INN
8922 milatuzumab
Synonyms
hLL1
IMMU-115
Database Links
Specialist databases
IMGT/mAb-DB 135
Other databases
Search PubMed clinical trials milatuzumab
Search PubMed titles milatuzumab
Search PubMed titles/abstracts milatuzumab
Wikipedia Milatuzumab
Comments
Milatuzumab is a humanized monoclonal antibody targeting CD74, a cell surface molecule which links the innate and adaptive immune responses by regulating the survival of macrophages and B cells. CD74 is also known as the invariant chain of major histocompatibility complex class II and acts as a receptor for macrophage migration inhibitory factor (MIF).
Milatuzumab may also be conjugated with doxorubicin creating the antibody-drug conjugate (ADC) hLL1-DOX (aka IMMU-110) [1].
Peptide sequence information for this antibody is available from its IMGT/mAb-DB link.