chlorpromazine

Ligand id: 83

Name: chlorpromazine

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 2
Hydrogen bond donors 0
Rotatable bonds 4
Topological polar surface area 31.78
Molecular weight 318.1
XLogP 4.46
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes (source: FDA (1957))
IUPAC Name
3-(2-chlorophenothiazin-10-yl)-N,N-dimethylpropan-1-amine
International Nonproprietary Names
INN number INN
183 chlorpromazine
Synonyms
chlorpromazine HCl
Largactil®
Thorazine®
Database Links
BindingDB Ligand 50001888
CAS Registry No. 50-53-3
ChEBI CHEBI:3647
ChEMBL Ligand CHEMBL71
DrugBank Ligand DB00477
NURSA Ligand 10.1621/KVEDIV62XD
PharmGKB Drug PA448964
PubChem CID 2726
RCSB PDB Ligand Z80
Search Google for chemical match using the InChIKey ZPEIMTDSQAKGNT-UHFFFAOYSA-N
Search Google for chemicals with the same backbone ZPEIMTDSQAKGNT
Search PubMed clinical trials chlorpromazine
Search PubMed titles chlorpromazine
Search PubMed titles/abstracts chlorpromazine
Wikipedia Chlorpromazine
Comments
Chlorpromazine was the first antipsychotic drug to be discovered. It is one of the most sedating of the typical antipsychotics and also causes antimuscarinic effects.