[11C]GSK215083

Ligand id: 8430

Name: [11C]GSK215083    

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 0
Rotatable bonds 3
Topological polar surface area 61.89
Molecular weight 385.13
XLogP 3.02
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
3-(3-fluorophenyl)sulfonyl-8-(4-methylpiperazin-1-yl)quinoline
Database Links
CAS Registry No. 887923-36-6 (source: PubChem)
PubChem CID 11696674
Search Google for chemical match using the InChIKey PXVJEDOZGDZJQY-BJUDXGSMSA-N
Search Google for chemicals with the same backbone PXVJEDOZGDZJQY
Comments
[11C]GSK215083 is used as a PET radioligand, to allow in vivo imaging of serotonin 5-HT6 receptor distribution [2]. GSK215083 is a 5-HT6 receptor antagonist with a lipophilicity profile permitting brain penetrance [1].