SKF-83959

Ligand id: 8443

Name: SKF-83959

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 1
Hydrogen bond donors 2
Rotatable bonds 1
Topological polar surface area 43.7
Molecular weight 317.12
XLogP 4.66
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
IUPAC Name
6-chloro-3-methyl-1-(3-methylphenyl)-1,2,4,5-tetrahydro-3-benzazepine-7,8-diol
Synonyms
SKF83959
Database Links
ChEMBL Ligand CHEMBL574558
PubChem CID 133538
Search Google for chemical match using the InChIKey JXMYTVOBSFOHAF-UHFFFAOYSA-N
Search Google for chemicals with the same backbone JXMYTVOBSFOHAF
Search UniChem for chemical match using the InChIKey JXMYTVOBSFOHAF-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone JXMYTVOBSFOHAF
Comments
Some substituted benzazepines such as SKF-83959 are G-protein biased agonists of the dopamine D1 receptor and fail to activate arrestin recruitment [1].