demcizumab

Ligand id: 8451

Name: demcizumab

Classification
Compound class Antibody
International Nonproprietary Names
INN number INN
9572 demcizumab
Synonyms
OMP-21M18
Database Links
Specialist databases
IMGT/mAb-DB 415
Other databases
Search PubMed clinical trials demcizumab
Search PubMed titles demcizumab
Search PubMed titles/abstracts demcizumab
Wikipedia Demcizumab
Comments
Demcizumab is a humanised IgG2 monoclonal antibody targeting DLL4 (delta-like 4 (Drosophila)), a membrane bound Notch receptor ligand expressed predominantly on vascular endothelial cells.
Peptide sequence information for this antibody is available from its IMGT/mAb-DB record. A BLAST search using the peptide sequence of the variable region of the heavy chain forming demcizumab reveals US7750124 B2 as the covering patent [1].