tremelimumab

Ligand id: 8462

Name: tremelimumab

Classification
Compound class Antibody
Ligand families/groups Immune checkpoint modulators
International Nonproprietary Names
INN number INN
8716 tremelimumab
Synonyms
CP-675 | CP-675,206 | CP-675206 | ticilimumab
Database Links
Specialist databases
IMGT/mAb-DB 248
Other databases
GtoPdb PubChem SID 252166672
Search PubMed clinical trials tremelimumab
Search PubMed titles tremelimumab
Search PubMed titles/abstracts tremelimumab
Wikipedia Tremelimumab
Comments
Tremelimumab is a fully human investigational monoclonal antibody targeting cytotoxic T-lymphocyte-associated protein 4 (CTLA4, CD152). Tremelimumab was designed as an antineoplastic agent. A BLAST sequence alignment matches tremelimumab to patent US 6682736, and identifies antibody clone 11.2.1 [2].