amelubant

Ligand id: 8463

Name: amelubant

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 3
Rotatable bonds 13
Topological polar surface area 100.87
Molecular weight 538.25
XLogP 9.67
No. Lipinski's rules broken 2

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Is prodrug? Yes
Active form BIIL 260
IUPAC Name
ethyl (NZ)-N-[amino-[4-[[3-[[4-[2-(4-hydroxyphenyl)propan-2-yl]phenoxy]methyl]phenyl]methoxy]phenyl]methylidene]carbamate
International Nonproprietary Names
INN number INN
8101 amelubant
Synonyms
BIIL 284
BIIL-284
Database Links
PubChem CID 60096302
Search Google for chemical match using the InChIKey SBVYURPQULDJTI-UHFFFAOYSA-N
Search Google for chemicals with the same backbone SBVYURPQULDJTI
Search PubMed clinical trials amelubant
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Comments
Amebulant is a leukotriene B4 (BLT1) receptor antagonist prodrug [1].