brolucizumab

Ligand id: 8713

Name: brolucizumab

Classification
Compound class Antibody
International Nonproprietary Names
INN number INN
10053 brolucizumab
Synonyms
ESBA-1008
ESBA1008
Database Links
Specialist databases
IMGT/mAb-DB 536
Other databases
Search PubMed clinical trials brolucizumab
Search PubMed titles brolucizumab
Search PubMed titles/abstracts brolucizumab
Comments
Brolucizumab is an investigational single-chain variable fragment (scFv) anti-VEGF antibody targeting vascular endothelial growth factor A (VEGFA). This immunobinder was derived from a humanised anti-VEGFA rabbit monoclonal [2].
Peptide sequence and secondary structural information are available from brolucizumab's IMGT/mAb-DB record.
Peptide sequence alignment analysis of patented peptide sequences using the heavy chain variable region of brolucizumab identifies a 100% match with SEQ ID NO: 164 in patent US8349322 B2 [1].