angiopoietin-like 3

Ligand id: 8716

Name: angiopoietin-like 3

Abbreviated name: ANGPTL3

Species: Human

Compound class Endogenous peptide in human, mouse or rat
Gene symbol Gene name Species Precursor protein name Synonyms
ANGPTL3 angiopoietin like 3 Human angiopoietin-related protein 3 preproprotein angiopoietin 5, angiopoietin-like 3
Database Links
UniProtKB Q9Y5C1 (Hs)
ANGPTL3 is prodominantly secreted in the liver, and has a pro-angiogenic function. The mature peptide is 444 amino acids long, and can be cleaved to form two functionally different sub-peptides: an N-terminal coiled-coil domain-containing chain (involved in lipid metabolism) and a C-terminal fibrinogen chain (angiogenic function).