glembatumumab vedotin

Ligand id: 8926

Name: glembatumumab vedotin

Classification
Compound class Antibody
International Nonproprietary Names
INN number INN
10123 glembatumumab vedotin
Synonyms
CDX-011
CR011-vcMMAE
Database Links
Specialist databases
IMGT/mAb-DB 565
Other databases
Search PubMed clinical trials glembatumumab vedotin
Search PubMed titles glembatumumab vedotin
Search PubMed titles/abstracts glembatumumab vedotin
Wikipedia Glembatumumab vedotin
Comments
Glembatumumab vedotin is a fully human anti-gpNMB (transmembrane glycoprotein NMB; gene symbol GPNMB) monoclonal antibody-drug conjugate (ADC) carrying the antineoplastic toxin monomethyl auristatin E (MMAE; PubChem CID 11542188). Development and preclinical evaluation of this ADC is reported in [4].
Annotated peptide sequences for this antibody are available from its IMGT/mAb-DB record.