trevogrumab

Ligand id: 8929

Name: trevogrumab

Classification
Compound class Antibody
International Nonproprietary Names
INN number INN
10087 trevogrumab
Synonyms
REGN-1033 | REGN1033 | SAR-391786 | SAR391786
Database Links
Specialist databases
IMGT/mAb-DB 556
Other databases
Search PubMed clinical trials trevogrumab
Search PubMed titles trevogrumab
Search PubMed titles/abstracts trevogrumab
Comments
Trevogrumab is a fully human moncolonal antibody, being investigated for its potential to treat diseases/disorders which are ameliorated or improved by inhibition of myostatin (a.k.a. GDF8).
Peptide sequences and structural information for this antibody are available from its IMGT/mAb-DB record.
BLAST peptide searches of patented peptide sequences reveals exact matches between the heavy chain variable region (HCVR) and the light chain variable region (LCVR) of trevogrumab with sequences 360 and 368 respectively, from patent US8840894 B2 [3].