emactuzumab

Ligand id: 8944

Name: emactuzumab

Classification
Compound class Antibody
International Nonproprietary Names
INN number INN
9951 emactuzumab
Synonyms
RG7155
RO5509554
Database Links
Specialist databases
IMGT/mAb-DB 501
Other databases
Search PubMed clinical trials emactuzumab
Search PubMed titles emactuzumab
Search PubMed titles/abstracts emactuzumab
Comments
Emactuzumab is a humanized, IgG1κ anti-colony stimulating factor 1 receptor (CSF1R) monoclonal antibody, being investigated for its anti-cancer potential.
Peptide sequence and structural information for this antibody are available from its IMGT/mAb-db record.
Peptide sequence analysis using the heavy and light chain variable regions of emactuzumab reveals 100% matches to sequences 39 and 40 respectively from patent US20110165156 [1]. These two sequences belong to the clone named hMab 2F11-e7 (or simply 2F11) in the patent document.