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Molecular properties generated using the CDK
|Compound class||Synthetic organic|
|RCSB PDB Ligand||539|
|Search Google for chemical match using the InChIKey||ABGOSOMRWSYAOB-UHFFFAOYSA-N|
|Search Google for chemicals with the same backbone||ABGOSOMRWSYAOB|
|A-196 is a selective chemical probe for the methyltransferases suppressor of variegation 4-20 homologs 1 and 2 (SUV420H1 and SUV420H2), and is one of the compounds available from the Structural Genomics Consortium's epigenetic probes set. It was developed in collaboration with AbbVie.
SUV420H1 and SUV420H2 are responsible for di- and tri-methylating lysine 20 of histone H4 (H4K20).