eldelumab

Ligand id: 9047

Name: eldelumab

Classification
Compound class Antibody
International Nonproprietary Names
INN number INN
9746 eldelumab
Synonyms
BMS-936557
MDX-1100
Database Links
Specialist databases
IMGT/mAb-DB 463
Other databases
Search PubMed clinical trials eldelumab
Search PubMed titles eldelumab
Search PubMed titles/abstracts eldelumab
Comments
Eldelumab (BMS-936557 and formerly MDX-1100) is a a fully human monoclonal antibody targeting the chemokine CXCL10 (a.k.a. interferon-γ-inducible protein-10 or IP-10) [1]. It is being investigated for its anti-inflammatory action in autoimmune conditions.
BLAST peptide sequence analysis reveals exact matches with heavy and light chain variable regions claimed in patent US8258266, and identify eldelumab as clone 6A5 [1].