cinnarizine

Ligand id: 9072

Name: cinnarizine

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 2
Hydrogen bond donors 0
Rotatable bonds 6
Topological polar surface area 6.48
Molecular weight 368.23
XLogP 9.87
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes (source: UK (1989))
IUPAC Name
1-[di(phenyl)methyl]-4-(3-phenylprop-2-enyl)piperazine
International Nonproprietary Names
INN number INN
4272 cinnarizine clofibrate
Synonyms
R-1575
Stugeron®
Database Links
BindingDB Ligand 50017657
CAS Registry No. 298-57-7
ChEMBL Ligand CHEMBL43064
DrugBank Ligand DB00568
PubChem CID 1547484
Search Google for chemical match using the InChIKey DERZBLKQOCDDDZ-JLHYYAGUSA-N
Search Google for chemicals with the same backbone DERZBLKQOCDDDZ
Search PubMed clinical trials cinnarizine clofibrate
Search PubMed titles cinnarizine clofibrate
Search PubMed titles/abstracts cinnarizine clofibrate
Comments
Cinnarizine is used primarily for its anti-histaminic activity, but it also has anti-cholinergic and calcium channel blocking effects, which may account for some of its side-effects.The INN record for this drug specifies cinnarizine clofibrate (PubChem CID 6436096).