CO

Ligand id: 9531

Name: CO

Classification
Compound class Inorganic
Prodrug CORM-2
Synonyms
carbon monoxide
Database Links
ChEBI CHEBI:17245
PubChem CID 281
Comments
Carbon monoxide is naturally produced by the action of heme oxygenase 1 and 2, which convert heme into biliverdin and carbon monoxide, utilizing NADPH as cofactor. Carbon monoxide has received a great deal of clinical attention as a biological regulator. Clinical trials of small amounts of carbon monoxide as a drug are ongoing. CO-releasing molecules (CORMs) are in development for their potential antioxidant, anti-inflammatory, and anti-tumor properties [1].