risperidone

Ligand id: 96

Name: risperidone

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Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 4
Topological polar surface area 49.58
Molecular weight 410.21
XLogP 4.01
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes (source: FDA (1993))
Is prodrug? Yes
Active form paliperidone
IUPAC Name
3-[2-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]ethyl]-2-methyl-6,7,8,9-tetrahydropyrido[2,1-b]pyrimidin-4-one
International Nonproprietary Names
INN number INN
6085 risperidone
Synonyms
R-64-766 | R-64766 | Risperdal®
Database Links
BindingDB Ligand 50001885
CAS Registry No. 106266-06-2
ChEBI CHEBI:8871
ChEMBL Ligand CHEMBL85
DrugBank Ligand DB00734
PubChem CID 5073
Search Google for chemical match using the InChIKey RAPZEAPATHNIPO-UHFFFAOYSA-N
Search Google for chemicals with the same backbone RAPZEAPATHNIPO
Search PubMed clinical trials risperidone
Search PubMed titles risperidone
Search PubMed titles/abstracts risperidone
Search UniChem for chemical match using the InChIKey RAPZEAPATHNIPO-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone RAPZEAPATHNIPO
Wikipedia Risperidone
Comments
Risperidone is an atypical antipsychotic drug, functioning as a dopamine D2, serotonin 5-HT2 and α2-adrenoceptor antagonist.