domperidone

Ligand id: 965

Name: domperidone

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Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 7
Hydrogen bond donors 2
Rotatable bonds 5
Topological polar surface area 67.92
Molecular weight 425.16
XLogP 3.36
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Classification
Compound class Synthetic organic
Approved drug? Yes
IUPAC Name
6-chloro-3-[1-[3-(2-oxo-3H-benzimidazol-1-yl)propyl]piperidin-4-yl]-1H-benzimidazol-2-one
International Nonproprietary Names
INN number INN
4110 domperidone
Synonyms
Motilium® | Nauzelin® | R-33812
Database Links
BindingDB Ligand 50241107
CAS Registry No. 57808-66-9
ChEBI CHEBI:464745
ChEMBL Ligand CHEMBL219916
DrugBank Ligand DB01184
PubChem CID 3151
Search Google for chemical match using the InChIKey FGXWKSZFVQUSTL-UHFFFAOYSA-N
Search Google for chemicals with the same backbone FGXWKSZFVQUSTL
Search PubMed clinical trials domperidone
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Search UniChem for chemical match using the InChIKey FGXWKSZFVQUSTL-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone FGXWKSZFVQUSTL
Wikipedia Domperidone
Comments
Domperidone is an orally active, peripherally acting and selective antagonist of dopamine D2 and D3 receptors.