fasidotrilat

Ligand id: 6502

Name: fasidotrilat

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 7
Topological polar surface area 123.66
Molecular weight 311.08
XLogP 1.66
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Selectivity at human enzymes
Key to terms and symbols Click column headers to sort
Target Type Action Affinity Units Concentration range (M) Reference
Neutral endopeptidase Inhibitor Inhibition 8.3 pKi - 2
pKi 8.3 (Ki 5.6x10-9 M) [2]
Angiotensin-converting enzyme Inhibitor Inhibition 8.0 pKi - 1
pKi 8.0 (Ki 9.8x10-9 M) [1]