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Synonyms: MIG | monokine induced by gamma-interferon
Compound class:
Endogenous peptide in human, mouse or rat
Comment: CXCL9 is a chemokine. It acts as a chemoattractant for activated T cells and tumour-infiltrating leukocytes, but not for neutrophils or monocytes.
Species: Human
Ligand Activity Visualisation ChartsThese are box plot that provide a unique visualisation, summarising all the activity data for a ligand taken from ChEMBL and GtoPdb across multiple targets and species. Click on a plot to see the median, interquartile range, low and high data points. A value of zero indicates that no data are available. A separate chart is created for each target, and where possible the algorithm tries to merge ChEMBL and GtoPdb targets by matching them on name and UniProt accession, for each available species. However, please note that inconsistency in naming of targets may lead to data for the same target being reported across multiple charts. ✖ |
| Immunopharmacology Comments |
| CXCL9 is a chemoattractant for activated T cells and tumor-infiltrating leukocytes, but not for neutrophils or monocytes. |
| Immunopharmacology Disease | |||
| Disease | X-Refs | Comment | References |
| Localized scleroderma |
Disease Ontology:
DOID:8472 |
Serum and lesional levels of CXCL9 are elevated in localized scleroderma. The serum concentration positively correlated with disease activity. CXCL9 co-localizes with CD68+ dermal macrophages by double-staining immunohistochemistry. | 2 |
