The IUPHAR Guide to PHARMACOLOGY complete ligand list

All ligands in the database which are currently, or have been in the past, approved for human clinical use by a regulatory agency.

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Ligand name ID Synonyms
A Back to top
abaloparatide 8299 BA058, Tymlos®
abarelix 1188 Plenaxis®, PPI 149, R 3827
abatacept 6891 BMS-188667, CTLA4-IgG4m, Orencia®, RG-1046, RG-2077
abciximab 6584 7E3 antibody, antiGPIIBIIIa, C7E3, ReoPro®
abiraterone acetate 9288 Zytiga
acamprosate 7106 Campral®
acarbose 6791 BAY-G 5421, BAY-G-5421, Glucobay®, Precose®
acebutolol 7107 IL-17803A, Sectral®
acenocoumarol 9015 Sinthrome®, Sintrom®
acetazolamide 6792 Diamox®
acetohexamide 6793 Dymelor®
acetyldigitoxin 6794 acetyldiginatin, Acylanid®, alpha-acetyldigitoxin
aciclovir 4829 acyclovir, Zovirax®
acipimox 1596 Olbetam®
acitretin 7598 Ro-101670000, Soriatane®
aclidinium 7449 LAS W-330, LAS-34273, Tudorza Pressair®
ACTH  {Sp: Human} 3633 Acthar®, adrenocorticotropic hormone (1-39), corticotropin
adalimumab 4860 D2E7, FKB327, Humira®
adapalene 5429 Differin®
adenosine 2844 Adenocard®, Adenoscan®
adomeglivant 9479 LY2409021
(-)-adrenaline 479 adrenalin, Auvi-Q®, Epipen®, l-adrenaline, L-epinephrine, levoepinephrine
afatinib 5667 BIBW2992, Gilotrif®
aflibercept 6786 AVE0005, Eylea®, VEGF Trap, Zaltrap®, ziv-aflibercept
agomelatine 198 S20098, Thymanax®, Valdoxan®
ajmalicine 8746 delta-yohimbine, raubasine, rauvasan, rauwolfia alkaloid
albiglutide 7386 Eperzan®, GSK716155, Tanzeum®
alcaftadine 7587 Lastacaft®, R-89674
alectinib 7739 AF802, Alecensa®, CH5424802
alefacept 6787 Amevive®, BG 9273, BG 9712, BG-9273, BG-9712, Lfa3Tip
alemtuzumab 6770 campath 1H, Campath®, campath-1H, Lemtrada®
alendronate 3141 ABDP, BPH 1, Fosamax®, MK-217
alfentanil 7108 Alfenta®, R-39209, Rapifen®
alfuzosin 7109 SL-77499-10, SL-7749910, Uroxatral®
alglucosidase alfa 7561 Lumizyme®, Myozyme®, rhGAA
alimemazine 7237 Nedeltran®, trimeprazine
alirocumab 6744 Praluent®, REGN727, SAR-236553, SAR236553
aliskiren 4812 CGP-060536B, SPP100, Tekturna®
alitretinoin 2645 9-cis-retinoic acid, Panretin®, Toctino®
allopurinol 6795 Aloprim®, BW-56-158, BW-56158, Zyloprim®
almotriptan 7110 Axert®, LAS-31416, PNU-180638E
alogliptin 6319 Nesina®, SYR-322, Vipidia®
alosetron 2296 GR68755, Lotronex®
alpha-methyltyrosine 6956 Demser®, metyrosine, MK-781
alpha1-proteinase inhibitor 7487 A1AT, A1PI, alpha 1-antitrypsin, Aralast®, Prolastin®, serum trypsin inhibitor
alprazolam 7111 Niravam®, U-31889, Xanax®
alprenolol 563 Atenenol®
AlprolixTM 7373
altretamine 7112 Hexalen®
alvimopan 7471 ADL 8-2698, Entereg®
amantidine 4128 Symadine®
ambrisentan 3951 Letairis®
amcinonide 7060 CL-34699, Cyclocort®
amfenac 7565 AHR-5850D, Fenazox® (Japan)
amifampridine 8032 3,4-DAP, 3,4-diaminopyridine, Firdapse®, Zenas®
amiloride 2421 amiloride HCl, Midamor®
6-aminocaproic acid 6574 ε-aminocaproic acid, Amicar®, EACA
aminoglutethimide 7054 Cytadren®
aminohippuric acid 4810 PAH, Aminohippurate Sodium®, p-aminohippurate, p-aminohippuric acid, PAH
5-aminolevulinic acid 4784 5-aminolevulinate, D-aminolevulinic acid, Levulan®
amiodarone 2566 amiodarone hydrochloride, Cordarone®
amisulpride 963 (±)-amisulpride
amitriptyline 200 amitryptiline, Elavil®, Endep®
amlexanox 7113 AA-673, Amlexanox®, Aphthasol®, CHX-3673
amlodipine 6981 amlodipine besylate, amlodipine maleate, Norvasc®, UK-4834011
amoxapine 201 amoxipine, Asendin®
amphetamine 4804 (±)-amphetamine, Amphetamine Sulfate®, DL-amphetamine
anagrelide 7114 Agrylin®, BL-4162a, Xagrid®
anakinra 6972 antril, Kineret®
anastrozole 5137 Arimidex®
anileridine 7115 Leritine®
aniracetam 4133
anisindione 6960 Miradon®
antazoline 7116
apatinib 7648 YN968D1
apixaban 6390 BMS-562247, Eliquis®
apomorphine 33 Apokyn®, Ixense®, Uprima®
apraclonidine 7117 AL-02145, Iopidine®
apremilast 7372 CC-10004, Otezla®
aprepitant 3490 Emend®
aprotinin  {Sp: Bovine} 6570 basic protease inhibitor (BPI), BPTI, pancreatic trypsin inhibitor, Trasylol®
arformoterol 7479 Brovana®, YM-08316
argatroban 6385 DK-7419, GN-1600, Gn1600, MCI-9038, MD-805
aripiprazole 34 Abilify®, Aripiprex®, OPC 14597, OPC-14597
asenapine 22 ORG-5222, Saphris®, Sycrest®
aspirin 4139 Acetophen®, acetylsalicylic acid, Aspirin®
astemizole 2603 Hismanal®
ataluren 7341 PTC124
atenolol 548 Myocord®, Normiten®, Tenormin®
atezolizumab 7990 MPDL3280A, Tecentriq®
atomoxetine 7118 LY-139603, Strattera®
atorvastatin 2949 Lipitor®
atosiban 2213 Antocin®, d[D-Tyr(Et)2,Thr4,Orn8]vasotocin, d[D-Tyr(Et)2,Thr4]OVT, ORF22164, RWJ 22164, Tractocile®
atracurium 9537 atracurium besilate, atracurium dibesylate, BW 33A, Tracrium®
atropine 320 Atropen®, hyoscyamine
auranofin 6306 Ridaura®, SK&F-39162, SK-39162
avanafil 7448 Spedra®, Stendra®, TA-1790
avelumab 8735 Bavencio®, MSB-0010718C, MSB0010718C
axitinib 5659 AG 013736, AG-013736, AG013736, Inlyta®
azacitidine 6796 5-AZAC, 5-azacytidine, ladakamycin, U-18496, Vidaza®
azasetron 2285 Y-25130
azatadine 7119 Optimine®, SCH-10649
azathioprine 7120 Azasan®, BW-57-322, Imuran®
azelaic acid 7484 Azelex®, Finacea®, ZK-62498
azelastine 7121 A-5610, Astelin®, E-0659, Rhinolast®, W-2979M
azilsartan medoxomil 6900 Edarbi®, TAK 491
 
B Back to top
baclofen 1084 Baclon®, Kemstro®, Lioresal®
bambuterol 6601 Bambec®, Oxeol®
basiliximab 6879 CHI-621, L04AC02, SDZ-CHI-621, Simulect®
bazedoxifene 7355 Conbriza®, TSE-424, Viviant®, WAY-140424
beclometasone 7059 beclomethasone, SCH-18020W
beclometasone dipropionate 5894 beclomethasone dipropionate, Beconase®, Qnasl®, Vancenase®
belatacept 6892 BMS-224818, LEA29Y, Nulojix®
belimumab 6887 Benlysta®, hBlySmAb-1.1, lymphostat-B
belinostat 7496 Beleodaq®, PXD-101, PXD101
benazepril 6374 CGS-14824A, Lotensin®
benazeprilat 6375 CGS-14831
bendamustine 7478 Levact®, SDX-105, Treanda®
bendroflumethiazide 7122 Aprinox®, Naturetin®
benperidol 9215 Anquil®, MCN-JR-4584, R-4584
benserazide 5150 Madopar®, Ro 4-4602, serazide
benzatropine 7601 benztropine, benztropine mesylate, Cogentin®
benzonatate 7611 Tessalon®, Zonatuss®
benzquinamide 7124 P-2647, Quantril®
benzthiazide 7125 Aquatag®, Fovane®
bepotastine 7466 Talion®, TAU-284
bepridil 2337 CERM-1978, Vascor®
betamethasone 7061 SCH-4831
betanidine 7618 bethanidine, BW-467-C-60, Tenathan®
betaxolol 549 betaxolol HCl, Betoptic®, Kerlone®, SL-75212-10
betazole 7126 ametazole, Histalog®
bethanechol 297 Duvoid®, Urecholine®
bevacizumab 6771 Avastin®, rhuMAb-VEGF
bexarotene 2807 LGD1069, Targrexin®
bezafibrate 2668 Bezalip®
bicalutamide 2863 Calutide®, Casodex®
bimatoprost 1958 AGN 192024, LS-181817, Lumigan®
biperiden 7128 Akineton®, biperiden HCl, biperiden lactate
bisoprolol 7129 CL-297939, EMD-33512, Zebeta®
bivalirudin 6470 Angiomax®
blinatumomab 7384 Blincyto®, bscCD19xCD3, MEDI-538, MT-103, MT103
blonanserin 7670 AD 5423, AD-5423, Lonasen®
bortezomib 6391 peptide boronate, PS-341, Velcade®
bosentan 3494 RO 47-0203, Tracleer®
bosutinib 5710 Bosulif®, SK 606, SK-606, SKI 606
brain natriuretic peptide  {Sp: Human} 4890 BNP, BNP(1-32), BNP-32, brain natriuretic peptide 32, Natrecor®
brentuximab vedotin 6772 Adcetris®, anti-CD30 ADC SGN-35, SGN 35
bretylium 7130 ASL-603, bretylium tosylate, Bretylol®
brexpiprazole 7672 OPC 34712, OPC-34712
brigatinib 7741 Alunbrig®, AP-26113, AP26113, compound 11q [PMID: 27144831]
brimonidine 520 Alphagan®, Mirvaso®, UK14,304, UK14304
brinzolamide 6797 AL-4862, Azopt®
brivaracetam 9041 2-(2-oxo-4-propylpyrrolidin-1-yl)butanamide, Briviact®, compound 83α, UCB 34714, UCB-34714, UCB34714
brodalumab 7540 AMG-827, AMG827, Lumicef®, Siliq®
bromfenac 7131 AHR-10282B, Bromday®, Prolensa®, Xibrom®
bromocriptine 35 2-bromoergocryptine, bromocryptine, CB-154, Parlodel®
bromodiphenhydramine 7132 Ambodryl®
brompheniramine 7133 Bromfed®, brompheniramine maleate, Dimetapp®
buclizine 7134 UCB-4445
budesonide 7434 Entocort®, Pulmicort®, S-1320, Uceris®
bufexamac 7498 CP-1044-J3, Paraderm®, Parfenac®
bumetanide 4837 Bumex®, Burinex®, PF 1593, Ro 10-6338
bupivacaine 2397 DL-Bupivacaine, Marcain®, Sensorcaine®, W-7
bupranolol 550 Betadrenol®, BRN 2272923, Ophtorenin®, SK&F 16805-A
buprenorphine 1670 Buprenex®, Temgesic®
bupropion 7135 amfebutamone, BW-323, Wellbutrin®, Zyban®
buserelin 3860 buserelin acetate, HOE 766, HOE 766A, ICI 123215, Metrelef®, Suprefact®
buspirone 36 Buspar®, MJ-9022-1
busulfan 7136 Busulfex IV®, Myleran®
butabarbital 7137 Butisol®
butalbital 7138 alisobumal, allylbarbituric acid, itobarbital, tetrallobarbital
butorphanol 7591 butorphanol tartrate, LEVO-BC-2627
 
C Back to top
cabazitaxel 6798 Jevanta®, taxoid XRP6258, TXD 258, XRP-6258
cabergoline 37 Cabaser®, Caberlin®
cabozantinib 5887 BMS907351, Cabometyx®, Cometriq®, XL-184, XL184
caffeine 407 methyltheobromine
calcifediol 6921 25-hydroxyvitamin D3, calcidiol, Calderol, Ryaldee®, U-32070E
calcipotriol 2778 Dovonex®, MC903
calcitonin  {Sp: Human} 685 CT, LS-173874, thyrocalcitonin
calcitonin (salmon) 6973 CT (salmon), Miacalcin®
camostat 6432 ONO-3403
canagliflozin 4582 Invokana®, JNJ-28431754, TA-7284
canakinumab 6773 ACZ 885, ACZ885, Ilaris®
candesartan 587 CV-11974, TCV-116 (prodrug)
cangrelor 1776 AR-C69931MX, ARL69931, Kengreal®
capecitabine 6799 Ro-09-1978-000, Ro-091978000, Xeloda®
capromab 6878 capromab pendetide, CYT-351, CYT-356, Indium In 111 capromab, ProstaScint®
capsaicin 2486 Qutenza®
captopril 5158 Capoten®, SQ-14225
carazolol 569 BM-51052, conducton, corazolol
carbachol 298 Carbastat®, Carboptic®
carbamazepine 5339 calepsin, Carnexiv®, Tegretol®
carbidopa 5159 Duodopa®, Lodosyn®
carbinoxamine 7139 carbinoxamine maleate, Clistin®
carboplatin 7624 JM-8, Paraplatin®
carfilzomib 7420 Kyprolis®, PR-171
carglumic acid 7458 N-carbamylglutamate, Carbaglu®, OE-312
cariprazine 7671 RGH 188, RGH-188, Vraylar®
carisoprodol 7610 Soma®
carmustine 6800 BiCNU®, Carustine®
carphenazine 7140 Proketazine®, WY-2445
carprofen 7141 Ro-205720000
carteolol 7142 ABBOTT-43326, Cartrol®, Ocupress®, OPC-1085
carvedilol 551 Coreg®, DQ 2466, Eucardic®, SKF 105517
catumaxomab 7385 L01XC09, Removab®
cefadroxil 4831 Duricef®
ceftriaxone 5326 Rocephin®
celecoxib 2892 Celecox®, Onsenal®
celiprolol 9064 Celectol®, REV 5320, Selectol®, ST-1396, ST1396
cephalexin 4832 cefalexin, Ceporex®, Keflex®
cephalothin 8798 cefalotin sodium, Keflin®
cephradine 4830 cefradine, Infexin®, Velocef®
ceritinib 7397 compound 15b [PMID 23742252], LDK378, NVP-LDK378-NX, Zykadia®
cerivastatin 2950 Baycol®, Lipobay®
certolizumab pegol 6774 CDP870, Cimzia®, PHA 738144
ceruletide 7589 caerulein, cerulein, ceruletide diethylamine, Tymtran®
cetirizine 1222 Reactine®, Zyrtec®
(R)-cetirizine 1214 Vozet®, Xyzal®
cetrorelix 1190 Cetrotide®, SB-075
cetuximab 6882 C225, Erbitux®, IMC-225, IMC-C225
chenodeoxycholic acid 608 CDCA, Chenix®, chenodeoxycholate, Chenodiol®
chlophedianol 7324 SL-501, Ulone®
chlorambucil 7143 chlorbutin, Leukeran®
chlordiazepoxide 3370 chlordiazepoxide HCl, Librium®, Lygen®
chlormezanone 7323 chlormethazanone, Fenaprim®, Trancopa®
chloroprocaine 7145 chloroprocaine hydrochloride, Nesacaine®
chloroquine 5535 Aralen®, chloraquine, Malaquin®
chlorothiazide 4835 Diuril®
chlorotrianisene 7146 chlortrianisestrol, Tace®
chlorpheniramine 6976 chlorprophenpyridamine maleate, Phenetron®, Teldrin®
chlorpromazine 83 chlorpromazine HCl, Largactil®, Thorazine®
chlorpropamide 6801 Diabenese®, Glucamide®
chlorthalidone 7147 G-33182, Hygroton®
chlorzoxazone 2322 Paraflex®
cholic acid 609 CA, cholate, Cholbam
ciclesonide 7469 Alvesco®, Omnaris®, RPR-251526
cilastatin 5166 MK 0791, Primaxin®
cilazapril 6459 Inhibace®, Ro 31-2848006, Vascace®
cilazaprilat 6461 Ro 31-3113
cilnidipine 7767 FRC-8653
cilostazol 7148 OPC-13013, OPC-21, Pletal®
cimetidine 1231 cimetidine HCl, Tagamet®
cinacalcet 3308 AMG-073, Mimpara®, Sensipar®
cinnarizine 9072 R-1575, Stugeron®
ciprofibrate 3438 Lipanor®, Modalim®, WIN-35833
cisapride 240 Prepulsid®, Propulsid®
cisplatin 5343 Platinol®
citalopram 7547 Celexa®, Cipramil®, LU-10171B
cladribine 4799 Leustatin®, Litak®
clemastine 6063 HS-592, meclastin, Tavegil®, Tavist®
clevidipine 7468 Cleviprex®
clidinium 366 Quarzan®
clobazam 7149 Frisium®, H-4723, HR-376, LM-2717, Onfi®, Urbanol®
clobetasol propionate 7062 CCI-4725, Clobex®, Dermovate®, GR 2/925, Temovate®
clobetasone 9088 Eumovate®
clofarabine 6802 CAFdA, Cl-F-araA, Clolar®, Evoltra®
clofazimine 9184 Lamprene®
clofibrate 2667 Atromid-S®, AY-61123, ICI-28257
clomiphene 4159 Androxal®, Clomid®, clomifene, MER-41, MRL-41, Omifin®, RMI-16289
clomipramine 2398 Anafranil®, G-34586
clonazepam 6963 Klonopin®, Ro-5-4023, Ro-54023
clonidine 516 Catapres®, Kapvay®
clopidogrel 7150 Plavix®, SR-25990C
clorazepate 7548 4306 CB, Tranxene®
clotrimazole 2330 Canesten®, Lotrimin®
clozapine 38 Clorazil®, HF-1854
cobicistat 7535 GS-9350
cobimetinib 7626 cobimetinib butyrate, cobimetinib fumarate, Cotellic®, GDC-0973, XL-518, XL518
cocaine 2286
codeine 1673 Codicept®, methylmorphine
colchicine 2367 Colcrys®
colfosceril palmitate 2799 DPPC, Exosurf Neonatal®
conestat alfa 7627 rhC1INH, Ruconest®
conivaptan 2203 Vaprisol®, YM-087, YM087
corticotropin zinc hydroxide