Introduction

IUPHAR Home

"NC-IUPHAR" is the International Union of Basic and Clinical Pharmacology Committee on Receptor Nomenclature and Drug Classification. The mission for NC-IUPHAR was initiated in 1987 at the Xth International Congress of Pharmacology. In 1989, the Executive Committee of IUPHAR named Paul Vanhoutte (Hong Kong) as chairman of a revised and enlarged committee. This committee energetically expanded its activities and the number of subcommittees (to 33), eventually producing the first official compendium on the occasion of the XIIIth International Congress of Pharmacology at Munich in 1998. Robert Ruffolo (USA) was Chairman of NC-IUPHAR from 1998-2002. Michael Spedding (France) became Chairman in 2002 and was elected again in 2006 and 2010.

NC-IUPHAR has the objectives of:

  1. Issuing guidelines for the nomenclature and classification of all the (human) biological targets, including all the targets of current and future prescription medicines;
  2. Facilitating the interface between the discovery of new sequences from the Human Genome Project and the designation of the derived entities as functional biological targets and potential drug targets;
  3. Designating polymorphisms and variants which are functionally important;

Annual report

For more information on NC-IUPHAR's activities, please download the latest NC-IUPHAR annual report in PDF.

NC-IUPHAR membership

Executive Committee

Stephen Alexander, UK - Chair
Arthur Christopoulos, Australia - Deputy Chair
Anthony Davenport, UK - Funding Liaison
Doriano Fabbro, Switzerland - Industry Liaison
Adam Pawson, UK - Executive Secretary

Core Members

Stephen Alexander, UK
Arthur Christopoulos, Australia - GPCRs Liaison
John Cidlowski, USA - NHRs Liaison
Anthony Davenport, UK - Chair Evolving Pharmacology, GPCRs Liaison
Doriano Fabbro, Switzerland
Kozo Kaibuchi, Japan
Yoshikatsu Kanai, Japan
Francesca Levi-Schaffer, Israel
Eliot Ohlstein, USA - Editor
Joerg Striessnig, Austria - VGICs Liaison
John Peters, UK - LGICs Liaison
Alex Phipps, UK

Ex Officio

Sam Enna, USA - IUPHAR President
Michael Spedding, France - IUPHAR Secretary-General
Petra Thürmann, Germany - IUPHAR Treasurer
Simon Maxwell, UK - Educational Site Project Leader
Jamie Davies, UK - Database Chair/Principal Investigator
Joanna Sharman, UK - Senior Database Developer
Simon Harding, UK - Database Developer, Immunopharmacology
Adam Pawson, UK - Senior Database Curator
Elena Faccenda, UK - Database Curator
Christopher Southan, Sweden - Senior Cheminformatician/Curator
Toni Wigglesworth, UK - Project Administrator
Elspeth Bruford, UK - HGNC Group Coordinator
Amrita Ahluwalia, UK - BJP Editor-in-Chief

Past Chairs (ex officio)

Paul Vanhoutte, China
Robert Ruffolo, USA

Corresponding Members

Susan Amara, USA
Tom Bonner, USA (Past Core Member)
Michel Bouvier, Canada
Thomas Burris, USA
William Catterall, USA (Past Core Member)
Steven Charlton, UK
Moses Chao, USA
Mark Coles, UK
Steven L. Colletti, USA
Graham Collingridge, UK
Sir Colin T. Dollery, UK (Founder and Past Core Member)
Richard Eglen, UK
Steven Foord, UK
David Gloriam, Denmark
Gillian Gray, UK
Debbie Hay, New Zealand
Allyn Howlett, USA
Franz Hofmann, Germany
Yu Huang, Hong Kong
Ad P. Ijzerman, The Netherlands
Michael F. Jarvis, USA
Bong-Kiun Kaang, Korea
Eamonn Kelly, UK
Terry Kenakin, USA
Janos Kiss, Hungary
Stefan Knapp, Germany
Andrew Knight, UK
Chris Langmead, Australia
Vincent Laudet, France (Past Core Member)
Margaret (Mandy) MacLean, UK
Neil Marrion, UK
Fiona Marshall, UK
Alistair Mathie, UK
Ian McGrath, UK
Graeme Milligan, UK
Rick Neubig, USA (Past Core Member)
Stefan Offermanns, Germany
Richard Olsen, USA
Jean-Philippe Pin, France (Past Core Member)
Helgi Schiöth, Sweden
Graeme Semple, USA
David Searls, USA
Roland Staal, USA
Bart Staels, France
Katerina Tiligarda, Greece
Georg Terstappen, Germany
Mary Vore, USA

Clinical Translational Pharmacology Group (core member Sir Colin Dollery)

Ed Bullmore, UK
Robert Dow, UK
Garrett Fitzgerald, USA
Alex Phipps, UK
Patrick du Souich, Canada
David Webb, UK
Don Birkett, Australia

Subcommittees

NC-IUPHAR subcommittee membership and a list of database contributors may be found on the Contributors page.