"NC-IUPHAR" is the International Union of Basic and Clinical Pharmacology Committee on Receptor Nomenclature and Drug Classification. The mission for NC-IUPHAR was initiated in 1987 at the Xth International Congress of Pharmacology. In 1989, the Executive Committee of IUPHAR named Paul Vanhoutte (Hong Kong) as chairman of a revised and enlarged committee. This committee energetically expanded its activities and the number of subcommittees (to 33), eventually producing the first official compendium on the occasion of the XIIIth International Congress of Pharmacology at Munich in 1998. Robert Ruffolo (USA) was Chairman of NC-IUPHAR from 1998-2002. Michael Spedding (France) became Chairman in 2002 and was elected again in 2006 and 2010.

NC-IUPHAR has the objectives of:

  1. Issuing guidelines for the nomenclature and classification of all the (human) biological targets, including all the targets of current and future prescription medicines;
  2. Facilitating the interface between the discovery of new sequences from the Human Genome Project and the designation of the derived entities as functional biological targets and potential drug targets;
  3. Designating polymorphisms and variants which are functionally important;

Annual report

For more information on NC-IUPHAR's activities, please download the latest NC-IUPHAR annual report in PDF.

NC-IUPHAR membership

Executive Committee

Stephen Alexander, UK (Chair)
Arthur Christopoulos, Australia (Deputy Chair)
Anthony P. Davenport, UK (Funding Liaison)
Doriano Fabbro, Switzerland (Industry Liaison)
Adam J. Pawson, UK (Executive Secretary)

Core Members

Stephen Alexander, UK
Arthur Christopoulos, Australia (GPCRs Liaison)
John Cidlowski, USA (NHRs Liaison)
Anthony P. Davenport, UK (Chair Evolving Pharmacology, GPCRs Liaison)
Doriano Fabbro, Switzerland
Kozo Kaibuchi, Japan
Yoshikatsu Kanai, Japan
Francesca Levi-Schaffer, PharmD, PhD, Israel
Eliot H. Ohlstein, USA (Editor)
Joerg Striessnig, Austria (VGICs Liaison)
John A. Peters, UK (LGICs Liaison)
Alex Phipps, UK

Ex Officio

Sam J. Enna, USA (IUPHAR President)
Michael Spedding, France (IUPHAR Secretary-General)
Petra Thürmann, Germany (IUPHAR Treasurer)
Simon Maxwell, UK (Educational Site Project Leader)
Jamie Davies, UK (Database Chair/Principal Investigator)
Joanna L. Sharman, UK (Senior Database Developer )
Adam J. Pawson, UK (Senior Database Curator )
Elena Faccenda, PhD, UK (Database Curator )
Christopher Southan, Sweden (Senior Cheminformatician/Curator )
Simon Harding, UK (Database Developer, Immunopharmacology)
Toni Wigglesworth, UK (Project Administrator )
Elspeth Bruford, UK (HGNC Group Coordinator )
Amrita Ahluwalia, Prof, UK (BJP Editor-in-Chief )

Past Chairs (ex officio)

Paul Vanhoutte, China
Robert R. Ruffolo, USA

Corresponding Members

Susan Amara, USA
Tom I. Bonner, USA (Past Core Member)
Michel Bouvier, Canada
Thomas Burris, USA
William A. Catterall, USA (Past Core Member)
Steven Charlton, UK
Moses Chao, USA
Mark Coles, UK
Steven L. Colletti, USA
Graham L Collingridge, UK
Sir Colin T. Dollery, UK (Founder and Past Core Member)
Richard M. Eglen, UK
Stephen M. Foord, UK
David Gloriam, Denmark
Gillian Gray, UK
Debbie Hay, New Zealand
Allyn C. Howlett, USA
Franz Hofmann, Germany
Yu Huang, Hong Kong
Adriaan P. IJzerman, The Netherlands
Michael F Jarvis, USA
Bong-Kiun Kaang, Korea
Eamonn Kelly, Prof, UK
Terry Kenakin, USA
Janos Kiss, Hungary
Stefan Knapp, Germany
Andrew Knight, UK
Chris Langmead, Australia
Vincent Laudet, France (Past Core Member)
Margaret R. MacLean, UK
Neil Marrion, UK
Fiona Marshall, UK
Alistair Mathie, UK
Ian McGrath, UK
Graeme Milligan, UK
Richard Neubig, MD, PhD, USA (Past Core Member)
Stefan Offermanns, Prof, Germany
Richard Olsen, USA
Jean-Philippe Pin, France (Past Core Member)
Helgi Schiöth, Sweden
Graeme Semple, USA
David Searls, USA
Roland Staal, USA
Bart Staels, Prof, France
Katerina Tiligarda, Greece
Georg Terstappen, Germany
Mary Vore, USA

Clinical Translational Pharmacology Group

Edward Bullmore, UK
Robert Dow, UK
Garrett Fitzgerald, USA
Alex Phipps, UK
Patrick du Souich, Canada
David J. Webb, Professor, UK
Don Birkett, Prof, Australia


NC-IUPHAR subcommittee membership and a list of database contributors may be found on the Contributors page.