G protein-coupled receptors (GPCRs)

  • Browse GPCR families and access overviews, key references and selective ligands
  • Follow the links for longer introductions and for detailed annotation on pharmacology, function, structure, physiology and clinical relevance of each receptor
  • View the list of GPCR families

Ion channels

Including:

  • Ligand-gated ion channels (LGICs)
  • Voltage-gated ion channels (VGICs)
  • Other ion channels
  • Browse ion channel families and access overviews, key references and selective ligands
  • Follow the links for longer introductions and for detailed annotation on pharmacology, function, structure, physiology and clinical relevance of each channel or subunit
  • View the list of ion channel families

Nuclear hormone receptors (NHRs)

  • Browse NHR families and access overviews, key references and selective ligands
  • Follow the links for detailed annotation on pharmacology, function, structure, physiology and clinical relevance of each receptor
  • View the list of NHR families

Kinases

  • Browse kinase subfamilies and access large-scale inhibitor screening data.
  • Access detailed clinical information for approved drug kinase inhibitors.
  • View the list of kinase families

Catalytic receptors

Transporters

Enzymes

  • Browse a subset of enzymes with pharmacological relevance and access overviews, key references and selective ligands
  • Additional data are provided for protein kinases
  • View the list of enzyme families

Other protein targets

The Concise Guide to PHARMACOLOGY 2015/16

A publication snapshot created from the database summary pages.

Access the table of contents

IUPHAR Database

The IUPHAR/BPS Guide to PHARMACOLOGY builds upon and replaces the original IUPHAR Committee on Receptor Nomenclature and Drug Classification Database (IUPHAR-DB)