clonidine

Ligand id: 516

Name: clonidine

IUPHAR Pharmacology Education Project (PEP) logo

View more information in the IUPHAR Pharmacology Education Project: clonidine

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 2
Topological polar surface area 36.42
Molecular weight 229.02
XLogP 2.4
No. Lipinski's rules broken 0

Molecular properties generated using the CDK
Classification
Compound class Synthetic organic
Approved drug? Yes (FDA (1974))
IUPAC Name
N-(2,6-dichlorophenyl)-4,5-dihydro-1H-imidazol-2-amine
International Nonproprietary Names
INN number INN
2624 clonidine
Synonyms
Catapres® | Kapvay®
Database Links
BindingDB Ligand 50016897
CAS Registry No. 4205-90-7
ChEBI CHEBI:46632
ChEMBL Ligand CHEMBL134
DrugBank Ligand DB00575
GtoPdb PubChem SID 135650112
PubChem CID 2803
RCSB PDB Ligand CLU
Search Google for chemical match using the InChIKey GJSURZIOUXUGAL-UHFFFAOYSA-N
Search Google for chemicals with the same backbone GJSURZIOUXUGAL
Search PubMed clinical trials clonidine
Search PubMed titles clonidine
Search PubMed titles/abstracts clonidine
Search UniChem for chemical match using the InChIKey GJSURZIOUXUGAL-UHFFFAOYSA-N
Search UniChem for chemicals with the same backbone GJSURZIOUXUGAL
Wikipedia Clonidine
Comments
Clonidine is an α2 adrenoceptor agonist.
The structure shown here is in the amino form. A tautomeric imino form, represented by CHEBI:3757 also exists.